In the vibrant digital landscape, the Domain Name System (DNS) serves as an invisible navigator, quietly underpinning the flow of data and ensuring seamless connectivity. As such, DNS security holds critical significance. To address this need, our project, "SmartSecure DNS 2.0", has been developed. Built upon China Mobile's robust DNS data infrastructure with "minute-level" computational power and powered by the innovative D-mamba model, we have established a cutting-edge DNS protection system capable of identifying and mitigating malicious domains in real-time. Compared to other similar systems, our innovation demonstrates three distinct advantages. ①Firstly, the data source is highly reliable, derived from nearly five years of comprehensive logs from China Mobile's DNS network. ②Secondly, our model offers superior precision, with extensive feature extraction that ensures high accuracy while minimizing resource consumption, making it more environmentally sustainable. ③Thirdly, the service coverage is significantly broader, enabling rapid deployment across all in-network users of China Mobile to effectively address complex and sophisticated cyber threats. We are confident that "SmartSecure DNS 2.0" will enhance DNS security and contribute to building a safer, more resilient digital future.